A study of biochemical profile of chronic renal failure patients in tertiary care hospital: a cross sectional study

Authors

  • Mehul Kaliya Shree M.P.Shah GMC, Saurashtra University
  • Mittal Rathod Department of Community Medicine, M.P. Shah GMC, Jamnagar, Gujarat, India
  • Aniruddha Gohel Department of Community Medicine, M.P. Shah GMC, Jamnagar, Gujarat, India
  • Ajay Tanna Department of Medicine, M.P. Shah GMC, Jamnagar, Gujarat, India
  • Manish Mehta Department of Medicine, M.P. Shah GMC, Jamnagar, Gujarat, India

DOI:

https://doi.org/10.18203/issn.2454-2156.IntJSciRep20151499

Keywords:

CKD, GFR, Biochemical profile

Abstract

Background: Chronic kidney disease (CKD) describes abnormal kidney function and/or structure. Investigations are focused on assessment of renal function and therefore stage of CKD, identification of the underlying cause and assessment of complications of CKD.Earliest identification of any deviation can help in early intervention & prevention of morbidity & mortality.

Methods: 50 patients of CKD admitted at GG Hospital, a tertiary care hospital, Jamnagar during period of 1 year, were included. Data were collected by means of interviewing the patients and serological investigations.  

Results: 24% patients had hyperglycemias & 36% patients had impaired glucose tolerance. Almost all biochemical markers were elevated. 86% (43) had High blood urea. All the patients had Serum creatinine level above the normal range for age & sex. 72% (36) patients had hyponatremia & 4% (2) patients had hypernatremia. 22% (11) patients had hypokalemia & 40% (20) patients had hyperkalemia. 38% (19) patients had hypocalcaemia & 6% (3) patients had hypocalcaemia.

Conclusions: There must be prescribed protocol for all CRF patients for estimating biochemical profile so that any complication can be identified at earliest & intervened to prevent morbidity & mortality. 

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References

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Clinical and laboratory manifestations of chronic kidney disease and uraemia. In: Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson JL, Loscalzo J, eds. Harrison’s principles of internal medicine. 18th ed. The McGraw-Hill Companies, Inc; 2011:2310-2315.

Udani A. Clinical profile of CRF patients: Dissertation submitted to Saurashtra university, Gujarat; 2006.

Hassan M. Aetiology, laboratory and clinical profile of chronic renal failure, Dissertation submitted to the Rajiv Gandhi university of health sciences, Karnataka, Bangalore; 2006.

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Published

2015-12-19

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Section

Original Research Articles