Published: 2022-01-25

Can the new SARS-CoV-2 variant of concern, Omicron, evade the immune system?

Abdullah Zaawari, Saajidah Khan


It's been less than a week since scientists in Botswana and South Africa warned the world about a rapidly spreading SARS-CoV-2 variant, known as Omicron now. Researchers and scientists from all over the world are racing to get a clear picture of the threat that the variant poses to the world. However, it may take weeks or even months to completely understand its transmissibility and severity, as well as its ability to evade vaccines and cause reinfections.


Omicron, COVID-19, Immune system

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World Health Organization. Update on Omicron. 2021. Available at item/28-11-2021-update-on-omicron. Accessed 5 December 2021.

World Health Organization. Classification of omicron (B.1.1.529): SARS-COV-2 variant of concern. 2021. Available at: news/item/26-11-2021-classification-of-omicron-(b.1.1.529)-sars-cov-2-variant-of-concern. Accessed 5 December 2021.

Callaway E, Ledford H. How bad is omicron? what scientists know so far. 2021. Nature News. Available at Accessed 5 December, 2021.

Pulliam RCJ, Van Schalkwyk C, Govender N, Von Gottberg A, Cohen C, Groome MJ et al. Increased risk of SARS-CoV-2 reinfection associated with emergence of the Omicron variant in South Africa. MedRxiv. 2021;1-43.

Schmidt F, Weisblum Y, Rutkowska M, Poston D, DaSilva J, Zhang F et al. High genetic barrier to SARS-CoV-2 polyclonal neutralizing antibody escape. Nature. 2021;600:512-6.