Brainstem glioma clinical features and treatment outcomes: a case series


  • Tavseef A. Tali Department of Radiation Oncology, Sher I Kashmir Institute of Medical Sciences, Soura, Srinagar, Jammu and Kashmir, India
  • Fiza Amin Department of Gynaecology and Obstetrics, SKIMS Medical College, Srinagar, Jammu and Kashmir, India
  • Nazir A. Khan Department of Radiation Oncology, Sher I Kashmir Institute of Medical Sciences, Soura, Srinagar, Jammu and Kashmir, India
  • Mushtaq A. Sofi Department of Radiation Oncology, Sher I Kashmir Institute of Medical Sciences, Soura, Srinagar, Jammu and Kashmir, India



BGs, Radiation, Temozolomide


A diverse category of gliomas that mostly affect youngsters are known as brainstem gliomas (BGs). The diffuse intrinsic pontine glioma (DIPG), exophytic medullary glioma, and tectal glioma can be divided into categories based on architecture and clinical behaviour. The most frequent BG is DIPG. The median age at start is 6.5 years, and the median survival is less than a year. The fact that adults with DIPG live longer suggests that their tumours are less aggressive and have physiologically distinct origins than those in children. Patients may appear with one or more of the following symptoms: ataxia, long tract signs, or malfunction of the cranial nerves. The majority of the pons is occupied by an infiltrative lesion on magnetic resonance imaging, and contrast enhancement is typically not noticeable. Fractionated radiation is the norm in medicine.



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