Effect of probiotics in the treatment of gastrointestinal symptoms in patients with scleroderma

Authors

  • Afsaneh Enteshari-Moghaddam Department of Internal Medicine, School of Medicine, Ardabil University of Medical Science, Ardabil, Iran
  • Shafieh Movassaghi Department of Rheumatology, Tehran University of Medical Science, Tehran, Iran
  • Abdolrahman Rostamian Department of Rheumatology, Tehran University of Medical Science, Tehran, Iran

DOI:

https://doi.org/10.18203/issn.2454-2156.IntJSciRep20161467

Keywords:

SSc, Gastrointestinal involvement, Probiotics

Abstract

Background: Treatment of gastrointestinal symptoms in patients with systemic sclerosis has been a challenge for years. Drugs, immunosuppressive or anti-fibrotic have always been associated with complications. The effectiveness of probiotics as live microorganisms of nonpathogenic always was to treat the symptoms.

Methods:In this clinical trial, 37 patients with systemic sclerosis with mild to severe symptoms in the intervention and control groups were studied. Inventory (UCLA SCTC GIT 2.0) was used for rating the severity of the gastrointestinal tract. Collected data was analysed by statistical methods using SPSS.19.

Results: Improvement was seen in total score after the use of probiotics in gastrointestinal reflux condition ((P=0.001), gastric distention (P =0.001), emotional function ((P=0.001), social.

Conclusions:This study showed that probiotics were significantly effective in treatment of gastrointestinal symptoms in patients with systemic sclerosis.

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Published

2016-05-19

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Original Research Articles