Spontaneous perforation of jejunal gastrointestinal stromal tumour presenting with multiple intraperitoneal abscess cavities: a case report and review of literature

Authors

  • Indrajit Rana Department of General Surgery, Shija Hospitals & Research Institute, Imphal, Manipur, India
  • Jugindra Sorokhaibam Department of General Surgery, Shija Hospitals & Research Institute, Imphal, Manipur, India

DOI:

https://doi.org/10.18203/issn.2454-2156.IntJSciRep20162810

Keywords:

GIST, Perforation, Abscess

Abstract

Gastrointestinal stromal tumours (GISTs) account for less than 1% of gastrointestinal tumours. Perforation of GIST is very rare (0.8%) and it is infrequently described in the literature. We report a case of 53 years old gentleman who had spontaneous perforation of jejunal GIST with multiple intraperitoneal abscess cavities which is unique and extremely rare.

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References

Hasegawa T, Matsuno Y, Shimoda T, Hirohashi S. Gastrointestinal stromal tumor: consistent CD117 immunostaining for diagnosis, and prognostic classification based on tumor size and MIB-1 grade. Hum Pathol. 2002;33(6):669-76.

Efremidou EI, Liratzopoulos N, Papageorgiou MS, Romanidis K. Perforated GIST of the small intestine as a rare cause of acute abdomen: surgical treatment and adjuvant therapy. Case report. J Gastrointestin Liver Dis. 2006;15:297-9.

Oida Y, Motojuku M, Morikawa G, Mukai M, Shimizu K, Imaizumi T, et al. Laparoscopic-assisted resection of gastrointestinal stromal tumor in small intestine. Hepatogastroenterology. 2008;55:146-9.

Connolly EM, Gaffney E, Reynolds JV. Gastrointestinal stromal tumors. Br J Surg. 2003;90:1178-86.

Miettinen M, Lasota J. Gastrointestinal stromal tumors–definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis. Virchows Arch. 2001;438:1-12.

Corless CL, Fletcher JA, Heinrich MC. Biology of gastrointestinal stromal tumors. J Clin Oncol. 2004;22:3813-25.

Miettinen M, Majidi M, Lasota J. Pathology and diagnostic criteria of gastrointestinal stromal tumors (GISTs): a review. Eur J Cancer. 2002;38(5):39-51.

DeMatteo RP, Lewis JJ, Leung D, Mudan SS, Woodruff JM, Brennan MF. Two hundred gastrointestinal stromal tumors: recurrence patterns and prognostic factors for survival. Ann Surg. 2000;231(1):51-8.

Emory TS, Sobin LH, Lukes L, Lee DH, O’Leary TJ. Prognosis of gastrointestinal smooth-muscle (stromal) tumors: dependence on anatomic site. Am J Surg Pathol. 1999;23(1):82-7.

Roberts PJ, Eisenberg B. Clinical presentation of gastrointestinal stromal tumors and treatment of operable disease. Eur J Cancer. 2002;38(5):37-8.

Aparicio T, Boige V, Sabourin JC, Crenn P, Ducreux M, Le Cesne A, et al. Prognostic factors after surgery of primary resectable gastrointestinal stromal tumours. Eur J Surg Oncol. 2004;30(10):1098-103.

Steigen SE, Bjerkehagen B, Haugland HK, Nordrum IS, Løberg EM, Isaksen V, et al. Diagnostic and prognostic markers for gastrointestinal stromal tumors in Norway. Mod Pathol. 2008;21:46-53.

Annaberdyev S, Gibbons J, Hardacre JM. Dramatic response of a gastrointestinal stromal tumor to neoadjuvant imatinib therapy. World J Surg Oncol. 2009;7:30.

Wilson SL, Wheeler WE. Giant leiomyoma of the small intestine with free perforation into the peritoneal cavity. South Med J. 1992;85:667-8.

Huang CC, Yang CY, Lai IR, Chen CN, Lee PH, Lin MT: Gastrointestinal stromal tumor of the small intestine: a clinicopathologic study of 70 cases in the postimatinib era. World J Surg. 2009;33:828-34.

Shah SN. Malignant gastrointestinal stromal tumor of intestine: a case report. Indian J Pathol Microbiol. 2007;50:357-9.

Kingham TP, DeMatteo RP: Multidisciplinary treatment of gastrointestinal stromal tumors. Surg Clin North Am. 2009;89:217-33.

Ulusan S, Koc Z, Kayaselcuk F. Spontaneously Ruptured Gastrointestinal Stromal Tumor With Pelvic Abscess: A Case Report and Review. Gastroenterology Research. 2009;2(6):361-3.

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Published

2016-08-06

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Section

Case Reports