DOI: http://dx.doi.org/10.18203/issn.2454-2156.IntJSciRep20181847

Study frequency of ABO and RH in patients with acute coronary syndrome referred to Ardabil city hospital

Bijan Zamani, Firouz Amani, Faranak Hadeei

Abstract


Background: Regarding the high prevalence, the increasing trend of acute coronary syndrome (ACS), the importance of etiological studies of diseases and the existence of some reports on the role of blood groups in the development of diseases, including IHD, in order to study the blood groups in patients with acute coronary syndrome and other factors, this research was conducted in Ardabil.

Methods: This is a descriptive study that was carried out from March 2016 to May 2017 in a Hospital of Ardabil on 500 patients selected randomly from patients admitted to cardiac care unit of Hospital. The criteria for entering the study were: All subjects over the age of 30 and both sexes were males and females who had myocardial infarction (MI), unstable angina (UA) based on history, examination, serial electrocardiography and measurement cardiac enzymes are given by a specialist physician and they are willing to participate in the study. Then, in the checklist for each patient, the blood type ABO and RH, the age, sex, and risk factors of the disease such as hypertension, diabetes, obesity, consumption smoking, high blood lipids, and family history of premature stenosis were extracted from the patient records and then analyzes by statistical methods in SPSS.19.  

Results: Of all patients, 60.2% were male and the mean age was 62.28 years. Hypertension with 61.6%, smoking with 37.4%, and hyperlipidemia with 23.4% were the most common risk factors among patients. The blood groups A and A+ were the most common type of blood type, but due to the higher prevalence of A blood group in healthy individuals living in Ardabil, there was no significant relation between ACS and blood groups.

Conclusions: Results showed that blood groups did not show a meaningful relationship with the incidence of ACS and did not find any association between severity of this syndrome and blood groups.


Keywords


Acute coronary syndrome, Myocardial infarction, Blood groups, Ardabil

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References


Amsterdam EA, Wenger NK, Brindis RG, Casey DE Jr, Ganiats TG, Holmes DR Jr, et al. AHA/ACC guideline for the management of patients with non-ST-elevation acute coronary syndromes: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. 2014;130(25):2354-94.

Torres M, Moayedi S. Evaluation of the acutely dyspneic elderly patient. Clin Geriatr Med. 2007;23(2):307–25.

Achar AS, Kundu S, Norcross AW. Diagnosis of acute coronary syndrome. Am Fam Physician. 2005;72(1):119- 26.

Bayer AJ, Chadha JS, Farag RR, Pathy MS. Changing presentation of myocardial infarction with increasing old age. J Am Geriatr Soc. 1986;34(4):263-6.

Paul SD, O'Gara PT, Mahjoub ZA, DiSalvo TG, O'Donnell CJ, Newell JB, et al. Geriatric patients with acute myocardial infarction. Cardiac factor profiles, presentation, thrombolysis, coronary interventions, and prognosis. Am Heart J. 1996;131(4):710-5.

Rittger H, Hochadel M, Behrens S, Hauptmann KE, Zahn R, Mudra H, et al. Age-related differences in diagnosis, treatment and outcome of acute coronary syndromes: results from the German ALKK registry. Eurointervention. 2012;7(10):1197-205.

Nobahar M, Vafaei A. Comparison of classic symptoms in acute coronary syndromes among young and old patients. J Qazvin Univ Med Sci. 2005;9(1):18-22.

Von Beckerath N, Koch W, Mehilli J, Gorchakova O, Braun S, Schömig A, et al. ABO lo O1 allele and risk of myocardial infarction. Blood Coagul Fibrinolysis. 2004;15:61-7.

Lee HF, Lin YC, Lin CP, Wang CL, Chang CJ, Hsu LA. Association of blood group A with coronary artery disease in young adults in Taiwan. Intern Med. 2012;51:1815-20.

Michell JR. An association between ABO blood group distribution and geographical differences in death-rates. Lancet. 1977;1:295-7.

O’Donnell J, Laffan MA. The relationship between ABO histo-blood group, factor VIII and von Willebrand factor. Transfus Med. 2001;11:343-51.

Garrison RJ, Havlik RJ, Harris RB, Feinleib M, Kannel WB, Padgett SJ. ABO blood group and cardiovascular disease: the Framingham study. Atherosclerosis. 1976;25:311-8.

Ray KK, Francis S, Crossman DC. Measurement of plasma von Willebrand factor in acute coronary syndromes and the influence of ABO blood group status. J Thromb Haemost. 2004;2:2053-4.

Bayer PM, Hotschek H, Knoth E. Intestinal alkaline phosphatase and the ABO blood group system - a new aspect. Clin Chim Acta. 1980;108:81-7.

Sheikh MK, Bahari MB, Yusoff NM, Knight A. Association of blood groups with prognosis in acute coronary syndrome. J College Physicians and Surgeons Pak. 2009;19(8):514-7.

Biranvand M, Assad Pour M. Dyslipidemia and coronary artery disease. J Shahid Beheshti Univ Med Sci. 2005;54(12):384-8.

Sakuma I, Kishimoto N, Oyama N, Saijo Y, Nawate S, Souma T,et al. Low High-Density Lipoprotein Cholesterol, Hypertension, Diabetes, but Not High Low-Density Lipoprotein Cholesterol as Predictors of Acute Coronary Syndrome in Northern Area of Japan: A Case-Control Study. JACC. 2004;13:1047-180.

Hammoudeh AJ, Al-Tarawneh H, Elharassis A, Haddad J, Mahadeen Z, Badran N, et al. Prevalence of conventional risk factors in Jordanians with coronary heart disease: The Jordan Hyperlipidemia and Related Targets Study (JoHARTS). Int J Cardiol. 2005;24(9):21-8.

Van Wyk JT. Identification of the four conventional cardiovascular disease risk factors by dutch general practitioners. Chest. 2005;128:2521-7.

Green SM, Vowels J, Waterman B, Rothrock SG, Kuniyoshi G. Leukocytosis: a new look at an old marker for acute myocardial infarction. Acad Emerg Med. 1996;3(11):1034-41.

Khan HA, Alhomida AS, Sobki SH, Moghairi AA, Koronki HE. Blood cell counts and their correlation with creatine kinase and C-reactive protein in patients with acute myocardial infarction. Int J Clin Exp Med. 2012;5(1):50-5.

Ghaemyan A, Haydari J. Relationship between leukocyte differential count and left ventricular systolic dysfunction after acute myocardial infarction. J Mazandaran Univ Med Sci. 2004;14(42):84-91.

Saravi M, Alizadeh Navaei R, Rouzbeh F, Montazeri M, Ashraf Vaghefi S. Evaluating correlation between neutrophil and congestive heart failure. J Qazvin Univ Med Sci. 2006;9(4):76-80.

Chen Y. Analysis of circulating cholesterol levels as a mediator of an association between ABO blood group and coronary heart disease. Circ Cardiovasc Genet. 2014;7:43–8.

Gong P, Li S, Luo SH, Zhang Y, Li XL, Guo YL, et al. High-sensitivity C-reactive protein mediates in part the impact of ABO blood group on coronary artery disease. Int J Cardiol. 2014;177:641–3.

Umesh N, khot M. prevalence of conventional risk factors with coronary heart disease. JAMA. 2003;290:898-904.

Deepak L, Gabril P. International prevalence, recognition and treatemtnt of cardiovascular risk factors. JAMA. 2006;295:180-9.

Januszkiewicz Ł, Szczerba E, Paszkowska P, Cacko A, Grabowski M, Sierdziński J, et al. Association of blood groups with prognosis in acute coronary syndrome. Pol Arch Med Wewn. 2013;123:460-6.

Miri R, Agha Hoseyni M, Farzaneh S. The Relationship between Blood Groups and Ischemic Heart Disease in Patients Admitted to Shaheed Beheshti University of Medical Sciences. Pajhohandeh. 2011;14(3):18-23.

Banerjee S, Datta UK. Relationship of ABO Blood Groups with Ischemic Heart Disease. Indian Medical Gazette. 2011: 430-433.

Whincup PH, Cook DG, Phillips AN, Shaper AG. ABO blood group and ischemic heart disease in British men. BMJ. 1990;300:1679-82.

Biswas S, Ghoshal PK, Halder B, Mandal N. Distribution of ABO blood group and major cardiovascular risk factors with coronary heart disease. Biomed Res Int. 2013;2013:782941.

Franchini M, Bonfanti C. Evolutionary aspects of ABO blood group in humans. Clin Chim Acta. 2015;444;66–71.

Sari I, Ozer O, Davutoglu V, Gorgulu S, Eren M, Aksoy M. ABO blood group distribution and major cardiovascular risk factors in patients with acute myocardial infarction. Blood Coagul Fibrin. 2008;19:231–4.

Amirzadegan A, Salarifar M, Sadeghian S, Davoodi G, Darabian C, Goodarzynejad H. Correlation between ABO blood groups, major risk factors, and coronary artery disease. Int J Cardiol. 2006;110:256–8.

Karabuva S, Carević V, Radić M, Fabijanić D. The association of ABO blood groups with extent of coronary atherosclerosis in Croatian patients suffering from chronic coronary artery disease. Biochem Med (Zagreb). 2013;23(3):351–9.

Capuzzo E, Bonfanti C, Frattini F, Montorsi P, Turdo R, Previdi M, et al. The relationship between ABO blood group and cardiovascular disease: results from the Cardiorisk program. Ann Transl Med. 2016;4(10):189.