Adenoid cystic carcinoma of lung: a very unusual presentation
Keywords:Adenoid cystic carcinoma, Lung, Surgery, Radiotherapy
Adenoid Cystic Carcinoma (ACC) is a rare malignancy of the lung arising from the main bronchial division, sub mucosal glands of large airways. Initially it was suspected as a non-resolving pneumonia, which did not respond to empirical antibiotics. Contrast Enhanced Computer Tomography (CECT) of thorax was suggestive of malignancy, bronchoscopic biopsy was suggestive of adenoid cystic carcinoma. The mainstay of treatment is surgical resection (lobectomy, pneumonectomy). As the tumor is radiosensitive, radiotherapy can be used following surgery in the treatment.
Travis WD, Travis LB, Devesa SS. Lung cancer. Cancer. 1995;75:191-202.
Spencer H. Pathology of the lung. In: Spencer H, eds. A Book. 4th ed. Oxford: Pergamon; 1985: 968-969.
Reid JD. Adenoid cystic carcinoma (cylindroma) of the bronchial tree. Cancer. 1952;5:685-94.
Moran CA, Suster S, Koss MN. Primary adenoid cystic carcinoma of the lung. A clinicopathologic and immunohistochemical study of 16 cases. Cancer. 1994;73:1390-7.
Mondal A, Saha DK. Primary adenoid cystic carcinoma of lung. A cliniciopathological study. Indian J Thorac Cardiovasc Surg. 2008;24:240-3.
Gallagher CG, Stark R, Teskey M. Atypical manifestations of pulmonary adenoid cystic carcinoma. Br J Dis Chest. 1986;80:396-9.
Albers E, Lawrie E, Harell JH, Yi ES. Trachebronchial adenoid cystic carcinoma: a clinicopathological study of 14 cases. Chest. 2004;125:1160-5.
Ratto GB, Alloisio A, Costa R, Chiaramondia M. Primary peripheral adenoid cystic carcinoma of the lung. A case report. Acta Chir Belg. 2003;103:414-5.
Grillo HC, Mathisen DJ. Primary tracheal tumors: Treatment and results. Ann Thorac Surg. 1990;49:69-77.
Alcedo JC, Fabrega JM, Arosemena JR, Urrutia A. Imatinib mesylate as treatment for adenoid cystic carcinoma of the salivary glands: report of 2 successfully treated cases. Head Neck. 2004;26:829-31.