Published: 2015-06-28

Carcinoma of colon in an adolescent: a case report with review of literature

Unmesh Vidyadhar Takalkar, Shilpa Balaji Asegaonkar, Umesh Kulkarni, Amol Jadhav, Suresh Advani, D. Nageshwar Reddy


Colorectal cancer is an extremely rare clinical entity in pediatric and adolescent age group. In the present case report, diagnosis and management of adenocarcinoma of colon in a teenager has been presented. A 15-year old boy without any predisposing factor was referred with gastrointestinal symptoms. With advanced diagnostic and therapeutic modalities, the case was treated successfully. Nonspecific vague symptoms of gastrointestinal system especially pain in abdomen, altered bowel habits if associated with weight loss should be meticulously evaluated further. Even in the absence of any predisposing conditions, high level of suspicion of CRC in children and adolescents is mandatory.


Colon cancer, Adolescent, Predisposing factors

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Ashutosh Mukherji, A. K. Rathi, Kanika Sharma, Vikash Kumar, Kishore Singh, A. K. Bahadur. A study on presentation and behavior of colo-rectal carcinoma in young Indian patients. Trop Gastroenterol. 2011;32(2):122-7.

Kayton ML. Cancer and pediatric inflammatory bowel disease. Semin Pediatr Surg. 2007;16:205-13.

Al-Tonbary Y, Darwish A, El-Hussein A, Fouda A. Adenocarcinoma of the colon in children: case series and mini-review of the literature. Hemato Oncol Stem Cell Ther. 2013;6:29-33.

Musa Ibrahim, Adamu Ladan Mu’azu, Kabir Ibrahim Getso, Binta Jibir Wudil, Mohammad Aminu Mohammad, Ali Bala Umar, et al. Carcinoma of the colon in children with metastases to the duodenum: report of two cases and management reflections. J Pediatr Surg Case Rep. 2014;2(3)133-40.

Oberto C, Schwarz KB, Zambidis E, Campbell AB, Paidas C, Lindyberg K, et al. Malignant peritoneal mesothelioma in a pediatric patient mimicking matory bowel disease. Dig Dis Sci. 2004;49:434e7.

D. Ashley Hill, Wayne L. Furman, Catherine A. Billups, Shannon E. Riedley, Alvida M. Cain, Bhaskar N. Rao, et al. Colorectal Carcinoma in Childhood and adolescence: a clinicopathologic review. J Clin Oncol. 2007;25:36:5808-14.

Ferrari A, Rognone A, Casanova M, Zaffignani E, Piva L, Collini P, et al. Colorectal carcinoma in children and adolescents: the experience of the Istituto Nazionale Tumori of Milan, Italy. Pediatr Blood Cancer. 2008;50:588-93.

Radhakrishnan CN, Bruce J. Colorectal cancers in children without any predisposing factors. A report of eight cases and review of literature. Eur J Pediatr Surg. 2003;13(1)66-8.

Seung Yeon Noh, Seung Young Oh, Soo-Hong Kim, Hyun-Young Kim, Sung-Eun Jung, Kwi-Won Park. Fifteen-year-old colon cancer patient with a 10-year history of ulcerative colitis World J Gastroenterol. 2013 Apr;19(15):2437-40.

Antonio Muccillo, Edson Marchiori, Cláudia Renata Penna, Regina Rodrigues Guimarães, Gláucia Zanetti, Guilherme Abdalla, et al. Colon mucinous adenocarcinoma in childhood: a case report with emphasis on image findings. Case Rep Med. 2010;2010:327634.

Iyad Sultan, Carlos Rodriguez-Galindo, Hani El-Taani, Guido Pastore, Michela Casanova, Gianfranco Gallino, et al. Distinct features of colorectal cancer in children and adolescents. Cancer. 2010;116:758-65.