Reversible thyrotoxic cardiomyopathy: a case report
Keywords:Thyrotoxicosis, Hyperthyroidism, Dilated cardiomyopathy
Hyperthyroidism significantly affects the hemodynamics of the cardiovascular system. It is associated with development of atrial fibrillation, high output cardiac failure, pulmonary hypertension and dilated cardiomyopathy (DCM). In this paper we report a case of thyrotoxicosis induced cardiomyopathy. She was a 54 year old woman who presented with cardiomegaly (dilatation of all four chambers of the heart) secondary to Graves’ disease. She was treated with anti-thyroid drugs, β Blockers and diuretic and her euthyroid status was restored in 6 weeks. A repeat echocardiogram done at this point of time showed normal cardiac function with normalization of ejection fraction. So this was a case of reversible thyrotoxic cardiomyopathy.
Biondi B, Kahaly GJ. Cardiovascular involvement in patients with different causes of hyperthyroidism. Nat Rev Endocrinol. 2010;6:431-43.
Nayak B, Burman K. Thyrotoxicosis and thyroid storm. Endocrinol Metab Clin North Am. 2006;35(4):663-86.
Vydt T, Verhelst J, De Keulenaer G. Cardiomyopathy and thyrotoxicosis: tachy-cardiomyopathy or thyrotoxic cardiomyopathy? Acta Cardiol. 2006;61(1):115-7.
Siu CW, Yeung CY, Lau CP, Kung AW, Tse HF. Incidence, clinical characteristics and outcome of congestive heart failure as the initial presentation in patients with primary hyperthyroidism. Heart. 2007;93(4):483- 7.
Goland S, Shimoni S, Kracoff O. Dilated cardiomyopathy in thyrotoxicosis. Heart. 1999;91:444-9.
Tsymbaliuk I, Unukovych D, Shvets N, Dinets A. Cardiovascular complications secondary to Graves’ disease: a prospective study from Ukraine. Plos One. 2015;10:e0122388.