International Journal of Scientific Reports https://www.sci-rep.com/index.php/scirep <p>International Journal of Scientific Reports is an open access, international, peer-reviewed multidisciplinary science and technology journal. The journal's full text is available online at https://www.sci-rep.com. International Journal of Scientific Reports is dedicated to publishing research from all areas of science and technology. The journal has a broad coverage of Medical sciences, Dental sciences, Physiotherapy, Biological sciences, Pharmaceutical sciences, Earth and environmental sciences, Physical sciences. International Journal of Scientific Reports is one of the fastest communication journals and articles are published online within short time after acceptance of manuscripts. The types of articles accepted include original research articles, review articles, editorial, news, case reports, short communications, correspondence, images, problem solving, perspectives and new updates. It is published monthly and available in print and online version.</p> <p><em><strong>Aims and scope</strong></em></p> <p><strong>Biological sciences</strong></p> <p>Cancer, Structural biology, Biophysics, Zoology, Systems biology, Evolution, Biological techniques, Stem cells, Neuroscience, Genetics, Microbiology, Biotechnology, Computational biology and bioinformatics, Physiology, Biochemistry, Psychology, Ecology, Developmental biology, Drug discovery, Plant sciences, Chemical biology, Molecular biology, Immunology, Cell biology</p> <p><strong>Health sciences</strong></p> <p>Pathogenesis, Risk factors, Biomarkers, Diseases, Signs and symptoms, Anatomy, Medical research, Health care, Health occupations, Dental sciences, Physiotherapy, Pharmaceutical sciences</p> <p><strong>Earth and environmental sciences</strong></p> <p>Planetary science, Environmental sciences, Environmental social sciences, Ecology, Climate sciences, Solid Earth sciences</p> <p><strong>Physical sciences</strong></p> <p>Optics and photonics, Astronomy and planetary science, Nanoscience and technology, Mathematics and computing, Materials science, Chemistry, Engineering, Physics</p> <p> </p> <p><strong>Print ISSN:</strong> 2454-2156</p> <p><strong>Online ISSN:</strong> 2454-2164</p> <p><strong>Issues: 12 per year</strong></p> <p><strong>Email:</strong> <a href="mailto:editor@sci-rep.com" target="_blank" rel="noopener">editor@sci-rep.com</a>, <a href="mailto:medipeditor@gmail.com" target="_blank" rel="noopener">medipeditor@gmail.com</a></p> <p><strong>Publisher:</strong> <a href="http://www.medipacademy.com" target="_blank" rel="noopener"><strong>Medip Academy</strong></a></p> <p><strong>DOI prefix: 10.18203</strong></p> <p>Medip Academy is a member of Publishers International Linking Association, Inc. (PILA), which operates <a href="http://www.crossref.org" target="_blank" rel="noopener">CrossRef (DOI)</a></p> <p> </p> <p><strong>Manuscript Submission</strong></p> <p>International Journal of Scientific Reports accepts manuscript submissions through <a href="https://www.sci-rep.com/index.php/scirep/about/submissions#onlineSubmissions" target="_blank" rel="noopener">Online Submissions</a>:</p> <p>About the Journal &gt; <a title="Online Submissions" href="https://www.sci-rep.com/index.php/scirep/about/submissions#onlineSubmissions" target="_blank" rel="noopener">Online Submissions</a></p> <p>Registration and login are required to submit items online and to check the status of current submissions.</p> <p>Please check out the video on our YouTube Channel:</p> <p>Steps to register and submit a manuscript:<br /><a href="https://youtu.be/YHX7eUWH7bk" target="_blank" rel="noopener">https://youtu.be/YHX7eUWH7bk</a></p> <p>Problem Logging In-Clear cookies:<br /><a href="https://youtu.be/WVjZVkjB2SQ" target="_blank" rel="noopener">https://youtu.be/WVjZVkjB2SQ</a></p> <p>If you find any difficulty in online submission of your manuscript, please contact editor at <a href="mailto:editor@sci-rep.com">editor@sci-rep.com</a></p> <p> </p> <p><strong>Abbreviation</strong></p> <p>The correct abbreviation for abstracting and indexing purposes is Int J Sci Rep.</p> <p><strong> </strong></p> <p><strong>Abstracting and Indexing information</strong></p> <p>The journal is indexed with</p> <p><strong><a href="https://journals.indexcopernicus.com/search/journal/issue?issueId=all&amp;journalId=43334" target="_blank" rel="noopener">Index Copernicus</a></strong>, </p> <p><strong><a href="https://imsear.searo.who.int/handle/123456789/162466" target="_blank" rel="noopener">Index Medicus for South-East Asia Region (WHO)</a></strong>,</p> <p><strong><a title="https://www.scilit.net/wcg/container_group/21988" href="https://www.scilit.net/wcg/container_group/21988" target="_blank" rel="noopener">Scilit (MDPI)</a></strong>,</p> <p><strong><a title="https://www.worldcat.org/title/international-journal-of-scientific-reports-online/oclc/1127451860&amp;referer=brief_results" href="https://www.worldcat.org/title/international-journal-of-scientific-reports-online/oclc/1127451860&amp;referer=brief_results" target="_blank" rel="noopener">OCLC (WorldCat)</a></strong>,</p> <p><a href="http://www.crossref.org/titleList/" target="_blank" rel="noopener">CrossRef</a>,</p> <p><a href="http://www.journalindex.net/?qi=International+Journal+of+Scientific+Reports" target="_blank" rel="noopener">Journal Index</a>,</p> <p><a href="https://scholar.google.co.in/" target="_blank" rel="noopener">Google Scholar</a>,</p> <p><a title="LOCKSS" href="http://localhost/index.php/scirep/gateway/lockss" target="_blank" rel="noopener">LOCKSS</a>, </p> <p><a href="http://jgateplus.com/search/login/" target="_blank" rel="noopener">J-Gate</a>,</p> <p><a href="http://www.sherpa.ac.uk/romeo/search.php?id=2295&amp;format=full&amp;fIDnum=%7c" target="_blank" rel="noopener">SHERPA/RoMEO</a>,</p> <p><a href="http://www.icmje.org/journals-following-the-icmje-recommendations/" target="_blank" rel="noopener">ICMJE</a>, </p> <p><a href="http://www.journaltocs.ac.uk/index.php?action=browse&amp;subAction=pub&amp;publisherID=3072&amp;journalID=35437&amp;pageb=1&amp;userQueryID=25467&amp;sort=&amp;local_page=1&amp;sorType=&amp;sorCol=1" target="_blank" rel="noopener">JournalTOCs</a>, </p> <p><a href="http://journalseeker.researchbib.com/view/issn/2454-2156" target="_blank" rel="noopener">ResearchBib</a>.</p> en-US medipeditor@gmail.com (Editor) editor@sci-rep.com (Editor) Wed, 23 Apr 2025 17:55:57 +0530 OJS 3.3.0.13 http://blogs.law.harvard.edu/tech/rss 60 Pattern of emergency laparotomy in El Obied Hospital, Western Sudan https://www.sci-rep.com/index.php/scirep/article/view/1512 <p><strong>Background:</strong> Emergency laparotomy is a common surgical procedure, performed for a wide variety of intra-abdominal pathologies.</p> <p><strong>Methods:</strong> this study is a prospective, descriptive for pattern of emergency laparotomy conducted at El Obeid Hospital during the period of one-year 2021. The data was collected by questionnaire from all patients who were subjected for emergency laparotomy and fulfilled the inclusion criteria.</p> <p><strong>Results:</strong> There were 72 patients, 45 males (62.5%) and 27 (37.5%) females, with male to female ratio 1.7: 1. The majority of the patients were less than 40 years of age (84.8%) and the main age ± standard deviation of 24.65±16.202 years. The common indications are traumatic acute abdomen found in 26 patients (36%), perforated hollow viscous in 26 patients (36%) and acute intestinal obstruction in 20 patients (27.8%). The major cause of perforated hollow viscous was acute appendicitis in 21 patients (81%). Four patients developed surgical site infection and one of them developed a partial burst abdomen. The mortality rate was 1.7%.</p> <p><strong>Conclusions:</strong> The most common indications for emergency laparotomy were abdominal trauma, perforated appendicitis and acute intestinal obstruction. The majority of the patients were discharged in good condition.</p> Abdulrahman Mohammed Abdulrahman Abouh, Mohammedbabalrahma Bashier Ahmed Koko, El Bushra Ahmed Doumi Copyright (c) 2025 International Journal of Scientific Reports https://www.sci-rep.com/index.php/scirep/article/view/1512 Wed, 23 Apr 2025 00:00:00 +0530 Susceptibility profile of the population to artemether, lumefantrine, dihydroartemisinin and piperaquine for samples transported in a formulated transport media and ethylenediamine tetraacetic acid anticoagulants: a study conducted in Maseno area, Western https://www.sci-rep.com/index.php/scirep/article/view/1537 <p><strong>Background:</strong> <em>In vitro</em> sensitivity testing is one of the preferred methods of measuring susceptibility and undertaking surveillance of antimalarial drug efficacy. This method is able to measure <em>Plasmodium falciparum</em> susceptibility to several antimalarial drugs simultaneously, away from the influence of host immune related factors. The technique is being transitioned to <em>ex vivo</em> requiring tests on fresh sample. Such <em>in vitro </em>studies of field <em>P. falciparum</em> have been attributed to diminished viability as they transition from host ecosystem to lab conditions due to lack of a proper medium to stabilize the parasites. It is therefore imperative to calibrate the sample stabilization media to reduce artificial effects to the assay This study was meant to evaluate the effect of a formulated transport medium (TM) on viability of <em>Plasmodium</em>. The study assayed standard clones (W2 and 3D7), field isolates and compared the results with other published findings to come up with antimalarial susceptibility profile of the region.</p> <p><strong>Methods:</strong> Blood samples were collected from 322 assenting individuals from Maseno division visiting Chulaimbo Sub county hospital and confirmed positive for malaria. Each sample, split in to EDTA versus TM was analysed for susceptibility to artemether (ART), lumefantrine (LUM), dihydroartemisinin (DHA) and piperaquine (PPQ) using malaria SYBR green assay. IC<sub>50</sub> was determined for each sample between TM and EDTA using dose response curves. &nbsp;</p> <p><strong>Results:</strong> Results showed that the IC<sub>50</sub> values of the field isolates in EDTA were higher although not significant (p=0.99, 0.74, 0.68, 0.82 for ART, LUM, DHA and PPQ respectively) than those in the TM. Among the clones, PPQ was the only drug with a high significant IC<sub>50 </sub>decrease (p&lt;0.001) in TM for the W2 and a moderately significant decrease (p=0.028) in EDTA for 3D7 clone.</p> <p><strong>Conclusions:</strong> Lower IC<sub>50</sub> values recorded by the field isolates against the antimalarials were indicative of their high susceptibility to the drugs.</p> Scolastica C. Korir Copyright (c) 2025 International Journal of Scientific Reports https://www.sci-rep.com/index.php/scirep/article/view/1537 Wed, 23 Apr 2025 00:00:00 +0530 Factors influencing COVID-19 preventive behaviour in South Indian region https://www.sci-rep.com/index.php/scirep/article/view/1538 <p><strong>Background:</strong> The World Health Organization (WHO) has identified COVID-19 as a novel lung condition caused by an emerging virus. Socioeconomic factors significantly influence preventive behaviours like handwashing, wearing masks, social distancing, coughing cover, and avoiding touching the face to reduce COVID-19 transmission. Aim was to determine factors influencing COVID-19 preventive behaviour among selected households.</p> <p><strong>Methods:</strong> The cross-sectional descriptive study with 700 samples was conducted from July 2023 to November 2024 that collected quantitative data using an interviewer-administered questionnaire that was converted to Open Data Kit, a mobile data tool in South Indian region. Objective of study was to determine the association between socio-demographics, knowledge and preventive COVID-19 behaviours in this township residence over the age of 18 years old. One-way analysis of variance (ANOVA), independent t-test, and multiple linear regression were used to analyse the data. &nbsp;</p> <p><strong>Results:</strong> The overall mean score of knowledge related to COVID-19 was 25.95±7.07, whereas 37.48±15.05 was for preventive behaviours. After multiple linear regression, participants who living in urban, single, passed high educational status, family members who had COVID-19 history, COVID-19 patients who had underlying diseases reported higher preventive behaviour where as participants who had co morbidity reported lower performing preventive COVID-19 behaviours. Those participants with higher knowledge scores reported higher preventive COVID-19 behaviours (β=0.312, p=0.000).</p> <p><strong>Conclusions:</strong> Public health interventions should utilize these experiences to effectively communicate and promote preventive measures, thereby enhancing the targeting and impactful nature of future infectious disease prevention efforts.</p> Paidi Shrivatsam, Sai Deepthi Janaki Rani Ivaturi, Ankur Gangahar, Karthiga Vasudevan, Musaab Abdalla Elhussein Copyright (c) 2025 International Journal of Scientific Reports https://www.sci-rep.com/index.php/scirep/article/view/1538 Wed, 23 Apr 2025 00:00:00 +0530 Membranous glomerulonephritis: a case report https://www.sci-rep.com/index.php/scirep/article/view/1521 <p>A clinical case is presented with the aim of performing an analysis that allows to provide timely and comprehensive care to patients diagnosed with kidney diseases such as membranous glomerulonephritis, characterized by edema of the lower limbs, fatigue, and loss of protein in the urine. The case is a 55-year-old male patient who came to the NAPOLEÓN DÁVILA CÓRDOVA hospital because of anasarca and dyspnea with medium to minimal effort. Paraclinical tests are performed where leukocytosis with neutrophilia, slight elevation of creatinine and CRP, proteinuria, with hypoalbuminemia are evident; abdominal ultrasound reports significant ascites. In this context of a patient with generalized edema plus proteinuria and reduced albuminemia, nephrotic syndrome is suspected, for which reason measures are initiated to achieve a negative balance and with the diagnostic suspicion, a renal biopsy is performed in which a membranous lesion pattern + PLA 2R positive in basal membranes is reported. Analyzing the presentation of the patient's symptoms, it can be classified as idiopathic. The importance of diagnosing membranous glomerulonephritis is demonstrated.</p> Henry Paolo Loor, Gabriel Loor Macias, Juan José Estrada, Aura Aveiga Cedeño, María Lisbeth Montesdeoca Copyright (c) 2025 International Journal of Scientific Reports https://www.sci-rep.com/index.php/scirep/article/view/1521 Wed, 23 Apr 2025 00:00:00 +0530