Crossed fused ectopic kidney in a patient with irritable bowel syndrome with diarrhea: a case report


  • Chanchal Kumar Ghosh Department of Gastroenterology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh
  • M. Ashiqur Rahman Department of Gastroenterology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh
  • Nowrin Tabassum Department of Gastroenterology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh
  • M. Mosharraf Hossain Dhaka Medical College, Dhaka, Bangladesh
  • Sumon Dey Department of Gastroenterology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh



Kidney, Ectopic, Urinary, Renal, Bladder


Irritable bowel syndrome (IBS) is the most commonly diagnosed gastrointestinal condition that reduces patients' quality of life. It has multifactorial etiology. Nowadays it is thought that more than one etiologic factor may contribute to heterogeneous symptoms of IBS. Crossed fused ectopic kidney is a condition where both kidneys are situated on one side and fused and drain bilaterally into the urinary bladder. Most often, it is discovered by chance when evaluating another illness. A drum-shaped bulge was discovered in the descending colon of an 18-year-old girl during the examination of a protracted period of abnormal bowel habits in the form of diarrhea, with normal overlying mucosa. On additional examination, an abdominal CT scan revealed that she had a fused left renal ectopia and an empty right renal fossa. In most of the crossed fused renal ectopia (CFRE) cases patient remains asymptomatic; in a few cases it is associated with renal agenesis, vascular malformation, incontinence, a palpable abdominal mass, urinary tract infection, high incidence of stone formation, and genital anomalies. In this case report, we emphasize on crossed fused kidney causes an external compression to the intestinal wall which may create increased visceral hypersensitivity resulting in irritable bowel syndrome with diarrhea (IBS-D) type symptoms.


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Everhart JE, Ruhl CE. Burden of digestive diseases in the United States part II: lower gastrointestinal diseases. Gastroenterology. 2009;136(3):741-54.

Lovell RM, Ford AC. Global prevalence of and risk factors for irritable bowel syndrome: a meta-analysis. Clin Gastroenterol Hepatol. 2012;10(7):712-21.

Cook WA, Stephens FD. Fused kidneys: morphologic study and theory of embryogenesis. Birth Defects Original Article Series. 1977;13(5):327-40.

Lacy BE, Mearin F, Chang L, Chey WD, Lembo AJ, Simren M, Spiller R. Bowel disorders. Gastroenterology. 2016;150(6):1393-407.

Tanaka Y, Kanazawa M, Fukudo S, Drossman DA. Biopsychosocial model of irritable bowel syndrome. J Neurogastroenterol Motility. 2011;17(2):131.

Wouters MM, Balemans D, Van Wanrooy S, Dooley J, Cibert-Goton V, Alpizar YA et al. Histamine receptor H1–mediated sensitization of TRPV1 mediates visceral hypersensitivity and symptoms in patients with irritable bowel syndrome. Gastroenterology. 2016;150(4):875-87.

Akbar A, Yiangou Y, Facer P, Walters JR, Anand P, Ghosh S. Increased capsaicin receptor TRPV1-expressing sensory fibres in irritable bowel syndrome and their correlation with abdominal pain. Gut. 2008;57(7):923-9.

Hughes PA, Harrington AM, Castro J, Liebregts T, Adam B, Grasby DJ et al. Sensory neuro-immune interactions differ between irritable bowel syndrome subtypes. Gut. 2013;62(10):1456-65.

McDonald JH, McClellan DS. Crossed renal ectopia. Am J Surg. 1957;93(6):995-1002.

Rahim TA, Mittal P. Crossed renal ectopia with a fused supernumerary kidney. Cureus. 2020;12(4).

Patel TV, Singh AK. Crossed fused ectopia of the kidneys. Kidney Int. 2007;73(5):662.

Bauer SB. Anomalies of the upper urinary tract. Campbell's Urol. 2002;1903-6.

Meola M, Petrucci I. Ecografia clinica e color doppler in nefrologia. Eureka. 2007.

Aguilera TC, Del Valle SJI, Martín GB, Portillo MJA, Gutiérrez BJL, Ballestero DR. Tumor renal en ectopia renal cruzada con fusión. Actas Urológicas Españolas. 2005;29(10):993-6.

Redman JF, Berry DL. Wilms' tumor in crossed fused renal ectopia. J Pediatr Surg. 1977;12(4):601-3.






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