DOI: http://dx.doi.org/10.18203/issn.2454-2156.IntJSciRep20222071

Prospective study for utilization review for multiple antibiotics prescribed in the specialty department in tertiary care teaching hospital

Sushanta K. Das, Varshini R. Ganta, Suvarna A., Sushma P. Kakarlamudi, Pranav S.

Abstract


Background: The aim of the work was a prospective study of utilization review for multiple antibiotics prescribed in the specialty department in a tertiary care teaching hospital.

Methods: A prospective study was conducted for 6 months in specialty department in a tertiary care teaching hospital.

Results: In the 6 months duration of the study, a total number of 96 prescriptions were analyzed. The 77 prescriptions were prescribed with Beta-lactam antibiotics. and remaining prescriptions were prescribed with 2, 3 and 4-5 different classes of antibiotics.

Conclusions: The result obtained from our study is for judgment use of antibiotics will reduce the burden of multi-drug resistance and thereby enable better patient management and limit patient morbidity and mortality.


Keywords


Antibiotics, Antibiotic resistance, Utilization review, Morbidity

Full Text:

PDF

References


Kourkouta L, Kotsittopoulo S, Papageorgiou M, Iliadis CH, Monios A. The rational use of antibiotics medicine. J Health Care Communications. 2017:2,4-36.

Meher BR, Mukharjee D Udayshankar. A study on antibiotic utilization pattern in a general medicine ward of a tertiary care teaching hospital. J Chem Pharmaceutical Res. 2014:6(7):1847-49.

Alfonso J. Alanis resistance to antibiotics. Are we in the post-antibiotic Era? Arch Med Res. 2005;36;697-705.

Rijal S, Kunwar SD, Dahal A, Gupta S. Knowledge of use of antibiotics, its resistance and consequences among students in private school. J Nepal Med Asso. 2018:56(212);740-44.

Llor B. Antimicrobial resistance risk associated with antibiotic overuse and initiatives to reduce the problem. Ther Adv Drug Saf. 2014;5(6);229-41.

Peamanik MD. Impact of overuse of antibiotics on human health. ResearchGate. 2016.

Parente DM, Morton J. Role of pharmacist in antimicrobial stewardship. Med Clin North Am. 2018;102(5);929-36.

Porco TC, Gao D, Scott JC, Shim E, Enanoria WT, Galvani AP, Lietman TM. When does overuse of antibiotics become a tragedy of the commons? PLos one. 2012;7(12):e46505.

Klompas M. Overuse of Broad-Spectrum Antibiotics for Pneumonia. JAMA Intern Med. 2020;180(4):485-6.

Tillekeratne LG, Bodinayake CK. Antibiotic overuse for Acute respiratory tract infections Era? A qualitative study of outpatient and their physicians. BMC Fam Pract. 2017;18(1):37.

Baltatzis M, Chandra Balan V. Antibiotic use in acute pancreatitis: An adult of current practice in a tertiary center. Panceratology. 2016;16(6):946-51.

Cesur S, Demiroz AP. Antibiotics and the mechanism of resistance to antibiotics. Med J Islamic World Academy Sci. 2013;21(4):138-42.

Odonkor ST, Addo K. Bacteria resistance of antibiotics: recent trends and challenges. Int Bio Med Res. 2011;2(4):1204-50.

Moser C, Lerche CJ, Thomsen K, Hartvig T, Schierbeck J, Jensen P et al. Antibiotic therapy as personalized medicine-general considerations and complicating factors. APMIS. 2019;127(5):361-71.

Machowska A, Lundborg CS. Drivers of Irrational Use of Antibiotics in Europe. Int J Environ Res Public Health. 2018;16(1):27.

Campion M, Scully G. Antibiotic use in the intensive care unit: optimization and De-Escalation. J Intensive Care Med. 2018:33(12);647-55.

Abhijit K, Jain P, Upadhyaya P, Shipra Jain S. Antibiotic Prescribing in Various Clinical Departments in a Tertiary Care Teaching Hospital in Northern India. J Clin Diagn Res. 2014;8(5):HC09-11.

Al-shimemeri A, Al-Ghadeer H, Memish Z. Antibiotic utilization pattern in a general medicine ward of a tertiary medical center in Saudi Arabia. Avicenna J Med. 2011:1(1):8-11.

Davies J, Davies D. Origin and evolution of antibiotic resistance. Microbiol Mol Biol Rev. 2010;74;417-33.

Roduit J, Jornod P, Dorta N, Blum AL, Dorta G. Antibiotic prophylaxis of infective endocarditis during digestive endoscopy: over and underuse in Switzerland despite professed adherence to guidelines. Endoscopy. 2002;34(4).

Erdeljic V, Francetic I, Sarini CV, Bilusic M, Huic M, Mercep I et al. Evaluation of justification for antibiotics at the internal medicine clinic of the clinical hospital in Zagreb. Acta Med Croatica. 2004;58(4);293-9.

Maraha B, Bonten M, Fiolet H, Stobberingh E. Trends in antibiotic prescribing in general internal medicine wards. Antibiotic use and indication for prescription. Clin Microbiol Infect. 2000;6(1);41-4.

EI Sayed MF, Tamim H, Jamal D, Mumtaz G, Melki I. National Collaborative Perinatal Neonatal Network (NCPNN). Prospective study on antibiotics misuse among infants with upper respiratory infections. European J Pediatr. 2009;168(6):667-72.

Ayyad S, Al-Owaisheer A, Al-Banwan F, Al-Mejalli A, Thalib L. Evidence-based practice in the use of antibiotics for respiratory tract infections in primary health centers in Kuwait. Med Princ Practice. 2010;19(5):339-43.

Odonkors S, Addo K. Bacteria resistance to antibiotics. Int J Biological Med Res. 2011;2(4):1204-10.

Ashrat M, Cook P. Antibiotic misuse in hospital, outpatient, and long-term care setting. North Carolina Med J. 2016,77(5):346-49.

Clor C, Bjerrum L. Antimicrobial resistance risk associated with antibiotic overuse and initiative to reduce the problem, the advance in drug safety. Ther Adv Drug Saf. 2014;5(6):229-41.

Barker AK, Brown K, Ahsanm, Safdar N. Social determination of antibiotic misuse: a qualitative study of community members in Haryana, India. BMC Public Health. 2017;17(1):333.

Madhu G, James E, Venu R. A study on the appropriateness of antibiotics used for gastrointestinal disorder in a Tertiary Care Hospital. Euro J Hospital Pharmaceutical Sci Pract. 2016;23(5):283-7.

Tomma PD, Avidc E, Li DX, Dzintars K, Cosgrove SE. Association of adverse event with antibiotic use in hospitalized patients. JAMA Int Med. 2017;177(9):1308-15.

Jindal AK, Pandya K. Antimicrobial resistance: A public health challenge. Med J Armed Forces India. 2015;71(2)178-81.

Ventola C. Pharmacy and therapeutics of the antibiotic resistance crisis Medi Media USA. PT. 2015;40(4):277-83.

Mitchell K, Miellet S, Fish J. The drivers of antibiotic use and misuse. BMC Public Health. 2019;19(17):1425-37.

Sakeena MHF, Alexandra A. Enhancing pharmacists role in developing countries to overcome the challenge of antimicrobial resistance. BMC Public Health. 2018;18(48):763-74.