Myoid hamartoma of breast: a rare case report with review of literature

Authors

  • Nimisha Dhankar Department of Pathology, Maulana Azad Medical College, New Delhi, India
  • Nita Khurana Department of Pathology, Maulana Azad Medical College, New Delhi, India
  • Jyoti Kumar Department of Radiology, Maulana Azad Medical College, New Delhi, India
  • Sushanto Neogi Department of Surgery, Maulana Azad Medical College, New Delhi, India

DOI:

https://doi.org/10.18203/issn.2454-2156.IntJSciRep20232911

Keywords:

Mammary hamatroma, Myoid hamartoma, Breast lump, BIRADS

Abstract

Myoid hamartomas of breast are extremely rare lesions with poorly defined pathogenesis. They are composed of differentiated mammary glandular and stromal structures with areas of smooth muscle differentiation. They are postulated to arise from walls of the blood vessels and/or muscularis mammillae of the areolae. They usual present as a well demarcated lump and it is difficult to diagnose them on clinical and radiological basis. Diagnosis requires demonstration of smooth muscle phenotype using immunohistochemistry by smooth muscle actin and desmin. Surgical resection is the curative treatment. We reported a case of myoid hamartoma in a 50-year-old postmenopausal lady with its clinical, radiological and histopathological discussion. The lesion presented as a painless lump and was initially reported as BIRADS 4a on mammography. Apart from the stroma showing spindle cell component with smooth muscle differentiation, the histopathology also showed epithelial changes including epithelial hyperplasia and columnar cell change.

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References

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Published

2023-09-27

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Section

Case Reports