Massive retroperitoneal leiomyosarcoma: a case report

Abstract

Soft tissue sarcoma is mesenchymal tumor of malignant in nature seen in body. Liposarcoma followed by leiomyosarcoma are most common type. Leiomyosarcoma (LMS) in retroperitoneum region develop from smooth muscle cell or from wall of large vein and detect clinically when attain huge size, causing symptom due to compression or displacement to surrounding structure. We are presenting case report of a 65 years old lady presented with progressive pain abdomen, distension, loss of weight and appetite for 1 year. Radiological investigation reveals a large bilobed intra-abdominal mass with no major vascular involvement. Patient underwent complete surgical excision with resection of surrounding structure and post operative period was uneventful. HPE and IHC of resected tumor were suggestive of Leiomyosarcoma. Leiomyosarcoma usually has slow and silent progression hence present clinically when compression or displacement of adjacent structure arises. It has malignant potential. Radiological investigation helps in deciding resection. R0 resection carries very good prognosis since chemo and radiotherapy has limited role in complete cure.