Concurrent small bowel gastrointestinal stromal tumor and colonic adenocarcinoma in an elderly patient: a case report

Abdullah Al-Sawat; Shumukh Abdullah Alkhammash; Naif Shaker Alnefaie; Hanan Sulaiman Althobaiti; Tamer M. Abdelrahman

doi:10.18203/issn.2454-2156.IntJSciRep20252949

Authors

Abdullah Al-Sawat Department of Surgery, College of Medicine, Taif University, Taif, Saudi Arabia
Shumukh Abdullah Alkhammash Department of Surgery, King Abdulaziz Specialist Hospital, Taif, Saudi Arabia
Naif Shaker Alnefaie Department of Surgery, King Abdulaziz Specialist Hospital, Taif, Saudi Arabia
Hanan Sulaiman Althobaiti College of Medicine, Taif University, Taif, Saudi Arabia
Tamer M. Abdelrahman Department of Surgery, College of Medicine, Taif University, Taif, Saudi Arabia

DOI:

https://doi.org/10.18203/issn.2454-2156.IntJSciRep20252949

Keywords:

Colonic adenocarcinoma, Gastrointestinal stromal tumor, Multiple primary malignancies, Synchronous tumors, Small bowel neoplasm

Abstract

We report here the case of a 68-years-old man with synchronous small bowel gastrointestinal stromal tumor (GIST) and colonic adenocarcinoma, an occurrence reported infrequently in the literature. The patient was found to have these 2 separate malignancies while undergoing surgical evaluation for constipation, abdominal pain and rectal bleeding. Contrast-enhanced CT and colonoscopy diagnostic evaluations revealed a mass in the colon causing near obstruction. The surgical management included subtotal colectomy for the colonic adenocarcinoma and resection of the small bowel GIST. Histopathologic examination confirmed a spindle cell GIST (low grade (G1)) and a well-differentiated colonic adenocarcinoma. This case highlights the need for careful and comprehensive evaluation for synchronous malignancies, particularly so in geriatric patients and potential pathogenic mechanisms for multiple primary tumors and respective management approaches. Optimal outcomes with resection require long-term follow-up, including radiologic surveillance and adjuvant therapy.

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