Accidental organophosphate poisoning in a child in Uyo, Nigeria: a public health alert


  • Echey Ijezie Department of Paediatrics, University of Uyo Teaching Hospital, P.M.B 1136, Uyo, Akwa Ibom State, Nigeria
  • Fadekemi Megbelayin Department of Paediatrics, University of Uyo Teaching Hospital, P.M.B 1136, Uyo, Akwa Ibom State, Nigeria
  • Kevin Edem Department of Paediatrics, University of Uyo Teaching Hospital, P.M.B 1136, Uyo, Akwa Ibom State, Nigeria
  • Augustina Elochukwu Ijezie Department of Community Health, University of Uyo Teaching Hospital, P.M.B 1136, Uyo, Akwa Ibom State, Nigeria



Accidental, Organophosphate, Poisoning, Child, Atropine, Awareness


Organophosphates are often constituents of pesticides and insecticides. Some of these products are sold by unregistered vendors on the streets and in market places in sub-Saharan Africa. When purchased, and improperly stored, children may easily have access to, and inadvertently consume them. The clinical features of organophosphate poisoning include diarrhoea, diaphoresis, urination, miosis, bronchorrhoea, bronchospasm, bradycardia, emesis, lacrimation and salivation. Atropine administration is an important cornerstone of the management of this condition, with a good outcome in this instance. A case of organophosphate poisoning is herein reported to illustrate the effect of the predisposing factors to accidental childhood poisoning. It is hoped that this will help make an urgent case to raise public awareness on the prevention of accidental childhood poisoning, as well as the enforcement of regulations on the production, labeling, distribution and sale of these organophosphate compounds.


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Alazab RM, Elmougy MT, Fayad RA, Abdelsalam HF, Mohamed AS. Risk factors of acute poisoning among children: A study at a poisoning unit of a university hospital in Egypt. South East Asia Journal of Public Health. 2012;2(2):41-7.

Ugwu GIM, Okperi BO, Ugwu EN, Okolugbo NE. Childhood poisoning in Warri, Niger Delta, Nigeria: A ten year retrospective study. Afr J Prm Health Care Fam Med. 2012;4(1):321:1-5.

Adnan LHM, Kamaldin J, Mohamad N, Salatore SA, Suhaimi R (2013).The Risk of Accidental Chemical Poisoning Cases among Children (≤12 Years Old) Admitted to Hospital University Sains Malaysia: 5 Years Review. J Clinic Toxicol. 2013;4:177.

Adejuyigbe EA, Onayade AA, Senbanjo IO, Oseni SE. Childhood poisoning at the Obafemi Awolowo University Teaching Hospital, Ile-Ife, Nigeria. Niger J Med. 2002;11(4):183-6.

Ochigbo SO, Udoh JJ, Antia-Obong OE. Accidental Childhood Poisoning in Calabar at the turn of the 20th Century. Nigerian Journal of Paediatrics. 2004;31(3):67-70.

Oguche S, Bukbuk DN, Watila IM. Pattern of hospital admissions of children with poisoning in the Sudano-Sahelian North eastern Nigeria. Niger J Clin Pract. 2007;10(2):111-5.

Osaghae DO, Sule G. Accidental Childhood Poisoning in Benin City: Still a Problem? CMS UNIBEN JMBR. 2013:12(2):19-26.

Izuora GI, Adeoye A. A Seven-Year Review of Accidental Poisoning in Children at a Military Hospital in Hafr Al Batin, Saudi Arabia. Ann Saudi Med. 2001;21(1-2):13-5.

Yakubu M, Ahmadu BU, Simon P, Yerima TS, Umaru IH, Dauda MI. Pattern Of Accidental Childhood Poisoning In University Of Maiduguri Teaching Hospital: A Sudan-Sahelian Region Of Northern Nigeria. International Journal of Phytopharmacy Research. 2013;4(2):59-63.

Al Hamzi AM. Patterns of Accidental Poisoning in Children in Jeddah, Saudi Arabia. Annals of Saudi Medicine. 1998;18(5):457-9.

Belonwu RO, Gwarzo GD, Usman MB. Accidental Childhood Non-Food Poisonings in Aminu Kano Teaching Hospital Kano, Northern Nigeria. Kanem Journal of Medical Sciences. 2009;3(2):1-4.

Shwe DD , Toma B , Pate SI, Adedeji I , Oguche S. Profile of Hospital Admissions of Childhood Poisoning at a North-Central Nigerian Tertiary Health Care Centre. Jos Journal of Medicine. 2013;7(2):5-11.

Ibrahim A. Rodenticide poisoning in an unusual setting and its management challenges in a resource‑limited setting: Report of three cases. Journal of Medicine in the Tropics. 2013;15(2):156‑15.

Waddell BL, Zahm SH, Baris D, Weisenburger DD, Holmes F, Burmeister LF, Cantor KP, Blair A. Agricultural Use of Organophosphate Pesticides and Risk of Non-Hodgkin's Lymphoma Among Male Farmers (United States). Cancer Causes and Control. 2001;12:509-17.

Okeniyi JA, Lawal OA. Accidental Poisoning with Otapiapia: a Local Organophasphate-Containing Rodenticide: A Case Report. The Nigerian Medical Practitioner. 2007;52(4):100-1.

Musa U, Hati SS, Mustapha A, Magaji G. Dichlorvos concentrations in locally formulated pesticide (Ota-piapia) utilized in northeastern Nigeria. Scientific Research and Essay. 2010;5(1):049-54.

Pesticides Action Network (PAN) Nigeria. Strategic Assessment of the Status of POPs Pesticides Trading in South Western Nigeria. 2007:1-52.

Sowmya SG, Shreedhara Avabratha K, Aby D Varghese, Sanjeeva Rai B. Poisoning in Children: Experience at a Tertiary Care Hospital in Mangalore. International Journal of Medical Science and Public Health. 2014;3(11):1418-20.

Roberts DM, Aaron CK. Managing acute organophosphorus pesticide poisoning. BMJ 2007;334:629-34.

Eddleston M. Patterns and problems of deliberate self-poisoning in the developing world. Q J Med 2000;93:715-31.

World Health Organisation [WHO]. International Programme on Chemical Safety: Poisoning Prevention and Management. Available online: Accessed: 17/02/2016.

Ramdev S, Grover N, Sharma R, Sharma H. Acute poisoning in children: seven year experience at a tertiary care hospital of North India. Curr Paediatr Res. 2011;15(1):65-8.

Bacha T, Tilahun B. A cross-sectional study of children with acute poisoning: A three-year retrospective analysis. World J Emerg Med. 2015;6(4):265-9.

Katz KD, Brooks DE. Organophosphate Toxicity. Available online: article/167726-overview#a5. 2016. Accessed: 15.02.2016

Zwiener RJ, Ginsburg CM. Organophosphate and Carbamate Poisoning in Infants and Children. Pediatrics 1998;81(1):121-6.

Van Heel W, Hachimi-Idriss S. Accidental organophosphate insecticide intoxication in children: a reminder. International Journal of Emergency Medicine 2011;4:1-4.

Lifshitz M, Shahak E, Sofer S. Carbamate and organophosphate poisoning in young children. Pediatr Emerg Care. 1999;15:102‑3.

Rajendiran C, Ravi G, Thirumalaikolundu Subramanian P. Organophosphate, Carbamate and Rodenticide Poisoning in Children. Indian Journal of Practical Pediatrics 2009;11(1):6-14.

Kaur I, Jayashree K, Hiranandani M, Singhi SC. Severe Organophosphate Poisoning in a Neonate. Indian Pediatrics, 1996;33:517-9.

Kumar SV, Fareedullah MD, Sudhakar Y, Venkateswarlu B, Kumar EA. Archives of Applied Science Research. 2010;2(4):199-215.

Opawoye AD, Haque T. Insecticide/Organophosphate Poisoning in Children. Annals of Saudi Medicine. 1998;18(2):171-2.

Eddleston M, Buckley NA, Eyer P, Dawson AH. Management of acute organophosphorus pesticide poisoning. Lancet. 2008;371(9612):597-607.






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