Dominance of Staphylococcus aureus in clinical specimens in Islami bank hospital, Rajshahi, Bangladesh
DOI:
https://doi.org/10.18203/issn.2454-2156.IntJSciRep20173091Keywords:
Methicillin-resistant Staphylococcus aureus, Clinical isolates, Catalase negative cocci, Coagulase negative staphylococci, Mortality, InfectionsAbstract
Background: Staphylococcus aureus is a medicologically important pathogenic bacteria which is largely responsible for the thousands of human health hazzards. This study investigated the incidence of Staphylococcus aureus in various clinical samples from in- and outpatients attending Islami Bank Hospital, Rajshahi, Bangladesh.
Methods: Clinical isolates from the hospital was confirmed as Staphylococcus aureus using standard bacteriological techniques. This study reports the isolation and identification of Staphylococcus aureus, coagulase negative staphylococci and catalase negative cocci in clinical samples at Islami Bank Hospital, Rajshahi, Bangladesh.
Results: Out of a total of 144 putative isolates of Staphylococci from urine, ear and wounds screened for Staphylococcus aureus, 87 of them were confirmed as S. aureus, 30 were coagulase negative staphylococci while 27 were catalase negative cocci. The high incidence of S aureus in this study compared to other staphylococci demonstrates the versatility and propensity of S. aureus to cause diseases.
Conclusions: This is worrisome because of the high mortality and morbidity often associated with infections of this bacterium. It therefore calls for proper handling of specimen suspected to contain the organism or patients who might be at risk of infection. This is to avoid transmission to other patients and healthy individuals especially health workers as they might constitute vehicles for the spread of the organism. Further studies are recommended because of the small sample size in this study. This would help to establish whether this was peculiar to the Islami Bank Hospital Rajshahi, Bangladesh or wide spread in other hospitals in the country.Metrics
References
Lowy FD. Staphylococcus aureus infection. N Engl J Med. 1998;339:520-32.
Diekema DJ, Pfller MA, Schmitz FJ, Smayevsky J, Bell J, Jones RN, Beach M. The Sentry participants Group: Survey of infections due to Staphylococcus species: frequency of occurrence and antimicrobial susceptibility of isolates collected in United States, Canada, Latin America, Europe and Western Pacific Region for the SENTRY Antimicrobial Surveillance Program, 1997–1999. Clin Infect Dis. 2001;32:114-32.
Javid AD, Manzoor AT, Jamal AK, Asif A, Mohammed AK, Mohammed K, et al. Molecular epidemiology of clinical and carrier strains of methicillin resistant Staphylococcus aureus (MRSA) in the hospital settings of north India. Ann Clin Microbiol Antimicrobials. 2006;5:22.
Olayinka BO, Bala HK, Ehinmidu JO, Onaolapo JA. Multidrug resistant Staphylococcus aureus isolates from poultry farms in Zaria, Nigeria. 14th International Symposium on Staphylococci and Staphylococcal Infections, Bath, UK; 2010:ISSSI2010.
Olukoya DK, Asielue JO, Olasupo NA, Ikea JK. Plasmid profiles and antibiotic susceptibility patterns of Staphylococcus aureus isolates from Nigeria. Afr J Med Sci. 1995;24(2):135-8.
Nworie A, Umeh N. Investigation of Urinary Tract Infectionamong High School Children in Abakaliki Metropolis. J Biomed Sci Nig. 2010;8(1 & 2).
Nworie A, Eze UA. Prevalence and Etiologic Agents of Urinary Tract Infections in Pregnancy in Abakaliki Metropolis. Continental J Med Res. 2010;4:18-23.
Kolawole DO, Bisi-Johnson MA, Shittu AO. Epidemiological analysis of clinical isolates Staphylococcus aureus in Ile-Ife, Nigeria. Pakistan J Bio Sci. 2005;8(7):1016-20.
Kopp BJ, Nix DE, Armstrong EP. Clinical and economic analysis of methicillin-susceptible and -resistant Staphylococcus aureus infections. Ann. Pharmacother. 2004;38:1377-82.
Lodise TP, McKinnon PS. Clinical and economic impact of methicillin resistance in patients with Staphylococcus aureus bacteremia. Diagn Microbiol Infect Dis. 2005;52:113-22.
Nixon M, Jackson B, Varghese P, Jenkins D, Taylor G. Methicillin-resistant Staphylococcus aureus on orthopaedic wards: incidence, spread, mortality, cost and control. J Bone Joint Surg Br. 2006;88:812-7.
Akindele AA, Adewuyi IK, Adefioy OA, Adedokun SA, Olaolu AO. Antibiogram and Beta-Lactamase Production of Staphylococcusaureus Isolates from Different Human Clinical Specimens in a Tertiary Health Institution in Ile-ife, Nigeria. Am-Eurasian J Sci Res. 2010;5(4):230-3.
Obiazi HAK, Nmorsi OPG, Ekundayo AO, Ukwandu NCD. Prevalence and antibiotic susceptibility pattern of Staphylococcusaureus from clinical isolates grown at 37 and 44 ºC from Irrua, Nigeria. Afr J Microbiol Res. 2007: 57-60.
Orji I, Nworie A, Eze UA, Agberotimi IO, Okereke EC, Azi SO.The prevalence and antimicrobial susceptibility profile of methicillin resistant Staphylococcus aureus isolates from clinical specimens in a Tertiary Hospital, South East Nigeria. Continental J Pharma Sci. 2012;6(1):23–9.
Baba T, Takeuchi F, Kuroda M, Yuzawa H, Aoki K, OguchiA, et al. Genome and virulence determinants of high virulence community-acquired MRSA. The Lancet. 2002;359(9320):18.
Rodrı´guez-Noriega E, Seas C, Guzma´n-Blanco M, Mejı´a C, Alvarez C. Bavestrello L, et al. Evolution of methicillin-resistant Staphylococcus aureus clones in Latin Ame. Int J Infect Dis. 2010;14(7):560-6.
