Lipid profile in patients with coronary heart disease
DOI:
https://doi.org/10.18203/issn.2454-2156.IntJSciRep20174619Keywords:
Coronary heart disease, LDL, HDL, TriglyceridesAbstract
Background: The lipid profile and their ratio are important in management and follow up of patients with coronary heart disease. We studied the lipid profile and their ratios with proven coronary artery disease.
Methods: It was retrospective study to determine the lipid profile and their ratios in patients with proven coronary artery disease at Shakuntala Pathology Lab., Nagpur. 200 patients were studied.
Results: Out of 200 patients studied, 126 (63%) were males while 74 (37%) were females. out of 126 males,12 (9.52%) had raised cholesterol values of >200 mg/dL. 20 (15.87%) had raised triglyceride values of >200 mg/dL. 30 (23.80%) had lower HDL values of <35 mg/dL. 5 (3.96%) had raised LDL values of >150 mg/dL. 90 (71.42%) had raised values of >3.5 for cholesterol to HDL ratio. Out of 74 female patients, 20 (27.02%) patients had raised cholesterol values. 12 (16.21%) patients had raised triglycerides values. 13 (17.56%) patients had lower HDL values. 6 (8.10%) patients had raised LDL values. 50 (67.56%) patients had raised values for cholesterol to HDL ratio.
Conclusions: Our study shows more prevalence of coronary heart disease in males than females. Hypercholesteremia and hypertriglyceridemia was more prevalent in females. HDL values were lowered in more number of males than females. LDL values were raised in more number of females than males. Total cholesterol to HDL ratio was raised in more number of males than females.
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References
Adak M, Shivapuri JN. Serum lipid and lipoprotein profile abnormality in predicting the risk of coronary artery disease in non-diabetic patients attending NMCTH, Birgunj. Nepal Med Coll J. 2010;12(3):158-64.
Goel PK, Bharti BB, Pandey CM, Singh U, Tewari S, Kapoor A. A tertiary care hospital-based study of conventional risk factors including lipid profile in proven coronary artery disease. Indian Heart J. 2003;55(3):234-40.
Rajmohan L, Deepa R, Mohan A, Mohan V, Association between isolated hypercholesterolemia, isolated hypertriglyceridemia and coronary artery disease in south Indian type 2 diabetic patients, Indian. 2000;52(4):400-6.
Castelli WP, Anderson K. A population at risk. Prevalence of high cholesterol levels in hypertensive patients in the Framingham Study. Am J Med. 1986;80(2):23-32.
Bush TL, Fried LP, Barrett-Connor E. Cholesterol, lipoproteins, and coronary heart disease in women, Clin Chem. 1988;34(8):60-70.
Assmann G, Davignon J, Fernández Cruz A, Gotto AM Jr, Jacotot B, Lewis B, et al. Women and ischemic cardiopathy. Rev Clin Esp. 1989;185(6):308-15.
LaRosa JC. Women, lipoproteins and cardiovascular disease risk. Can J Cardiol. 1990;6:23-9.
Haddad FH, Omari AA, Shamailah QM, Malkawi OM, Shehab AI, Mudabber HK, et al. Lipid profile in patients with coronary artery disease. Saudi Med J. 2002;23(9):1054-8.
Limbu YR, Rai SK, Ono K, Kurokawa M, Yanagida JI, Rai G, Gurung N. Lipid profile of adult Nepalese population, Nepal Med Coll J. 2008;10(1):4-7.
Erem C, Hacihasanoglu A, Deger O, Kocak M, Topbas M. Prevalence of dyslipidemia and associated risk factors among Turkish adults: Trabzon lipid study. Endocrine. 2008;34(1-3):36-51.
Sclavo M. Cardiovascular risk factors and prevention in women: similarities and differences. Ital Heart J Suppl. 2001;2(2):125-41.
Connelly PW, MacLean DR, Horlick L, O'Connor B, Petrasovits A, Little JA. Plasma lipids and lipoproteins and the prevalence of risk for coronary heart disease in Canadian adults. Canadian Heart Health Surveys Research Group. CMAJ. 1992;146(11):1977-87.
MacLean DR, Petrasovits A, Connelly PW, Joffres M, O'Connor B, Little JA. Plasma lipids and lipoprotein reference values, and the prevalence of dyslipoproteinemia in Canadian adults. Canadian Heart Health Surveys Research Group. Can J Cardiol. 1999;15(4):434-44.
