Facial paralysis probably related to systemic isotretinoin


  • Ömer Kutlu
  • İlknur Balta
  • Engin Karaarslan
  • Emine Esra Kıratlı Nalbant
  • Göğem İmren
  • Hatice M. Ekşioğlu




Facial paralysis, Isotretinoin, Drug withdrawal


We report a patient with severe acne who developed facial paralysis after two months of treatment with oral isotretinoin. Drug withdrawal resulted in a complete clinical recovery. Our case and a review of the literature indicate that oral isotretinoin might be capable of causing a dysfunction of predominantly sensory nerve fibers in some individuals. Clinicians should be aware of possible neurological sensorial symptoms during isotretinoin therapy.



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