DOI: http://dx.doi.org/10.18203/issn.2454-2156.IntJSciRep20195302

Adenoid cystic carcinoma at base of the tongue with rare cervical lymph node metastasis diagnosed on fine needle aspiration cytology

Richa Garg, Sunil Gupta

Abstract


Adenoid cystic carcinoma (ACC) is an uncommon malignant tumour of salivary glands. Occurrence at base of the tongue is rare. Distant metastasis is common, however, metastasis to regional lymph node is not seen commonly, but if occurs carries a bad prognostic value and lessens the average survival age of the patient. Fine needle aspiration cytology (FNAC) in such cases provides early diagnosis for rapid management of the patient. Review of literature shows that very occasional cases are reported with ACC at base of tongue with regional lymph node metastasis. Here, we present such a rare case of a 55 years old male patient with metastatic adenoid cystic carcinoma of cervical lymph node diagnosed on FNAC with primary at base of the tongue.


Keywords


Adenoid cystic carcinoma, FNAC, Base of tongue, Lymph node

Full Text:

PDF

References


Akhavan A, Navabii H, Saeb M. Adenoid cystic carcinoma of base of tongue. BMJ Case Rep. 2012; 2012.

Falk GA, El-Hayek K, Morris-Stiff G, Tuthill RJ, Winans CG. Adenoid cystic carcinoma of the base of the tongue: Late metastasis to the pancreas. Int J Surg Case Rep. 2011;2(1):1–3.

EC Carreiro, Filho FP, Costa FW. Adenoid cystic carcinoma of the tongue: Case report and literature review. Med Oral Patol Oral Cir Bucal. 2008;13:475–8.

Hsu HC, Huang EY, Wang CJ. Postoperative adjuvant radiotherapy for adenoid cystic carcinoma of the head and neck: treatment results and prognostic factors. Chang Gung Med J. 2003;26:646–53.

Brayer KJ, Frerich CA, Kang H, Ness SA. Recurrent Fusions in MYB and MYBL1 Define a Common, Transcription Factor-Driven Oncogenic Pathway in Salivary Gland Adenoid Cystic Carcinoma. Cancer Discov. 2016;6(2):176–87.

Xu B, Drill E, Ho A, Ho A, Dunn L, Prieto-Granada CN, et al. Predictors of Outcome in Adenoid cystic carcinoma of salivary glands: A clinicopathologic study with correlation between MYB fusion and protein expression. Am J Surg Pathol. 2017;41(10):1422-32.

Tumours of the oropharynx (base of tongue, tonsils, and adenoids). In: Naggar AK, Chan JKC and Grandis JR, Takata T, Slootweg PJ (eds). WHO Classification of Head and Neck Tumours. 4th edition. Lyon, IARC Press; 2017: 134-140.

Van Weert S, Reinhard R, Bloemena E. Differences in patterns of survival in metastatic adenoid cystic carcinoma of the head and neck. Head Neck. 2017;39(3):456-63.

Marks RA, Cramer HM, Wu HH. Fine-needle aspiration cytology of basaloid squamous cell carcinoma and small cell carcinoma-a comparison study. Diagn Cytopathol. 2013;41(1):81-4.

Conley J, Dingman DL. Adenoid cystic carcinoma in the head and neck (cylindroma). Arch Otolaryngol. 1974;100:81–90

Oplatek A, Ozer E, Agrawal A, Bapna S, Schuller DE. Patterns of recurrence and survival of head and neck adenoid cystic carcinoma after definitive resection. Laryngoscope. 2010;120:65–70.

Amit M, Binenbaum Y, Sharma K, Ramer N, Ramer I, Agbetoba A, et al. Incidence of cervical lymph node metastasis and its association with outcomes in patients with adenoid cystic carcinoma. An international collaborative study. Head Neck. 2015;37(7):1032-7.