DOI: http://dx.doi.org/10.18203/issn.2454-2156.IntJSciRep20205032

Anaesthesia for a child with glucose-6-phosphate-dehydrogenase deficiency: a case report

Baththirange Malaka Munasinghe, Srisothinathan Nimalan, Nishanthan Subramaniam, Sonali Goonetilleke

Abstract


Patients with glucose-6-phosphate-dehydrogenase (G6PD) deficiency are prone to acute haemolytic crisis during perioperative period, precipitated by oxidative stress and certain medications, which are common concurrences during this period. Careful peri-operative planning, judicious use of medication and postoperative monitoring plays a pivotal role in preventing complications in these patients. Here, we report a successful case of general anaesthesia in a child with G6PD deficiency.  


Keywords


Glucose-6-phosphate dehydrogenase deficiency, Oxidative stress, Acute haemolytic crisis

Full Text:

PDF

References


Elyassi AR, Rowshan HH. Perioperative management of the glucose-6-phosphate dehydrogenase deficient patient: a review of literature. Anesth Prog. 2009;56(3):86-91.

Cappellini MD, Fiorelli G. Glucose-6-phosphate dehydrogenase deficiency. Lancet. 2008;371 :64-74.

Altikat S, Ciftçi M, Büyükokuroğlu ME. In vitro effects of some anesthetic drugs on enzymatic activity of human red blood cell glucose 6-phosphate dehydrogenase. Pol J Pharmacol. 2002;54(1):67-71.

Cho H, Young Lee S, Hee Kim G. Anesthetic management of a patient with glucose-6-phosphate dehydrogenase deficiency undergoing robot-assisted laparoscopic surgery. A case report. Anesth Pain Medic. 2017;12:243-6.

Doshi CM, Tandale SR, Mohite SN, Nagaria A. Perioperative management in a case of glucose-6-phosphate dehydrogenase deficiency undergoing orthopaedic surgery. Saudi J Anaesth. 2015;9:490-1.

Valiaveedan S, Mahajan C, Rath GP, Bindra A, Marda MK. Anaesthetic management in patients with glucose-6-phosphate dehydrogenase deficiency undergoing neurosurgical procedures. Indian J Anaesth. 2011;55(1):68-70.

Sharma V, Verma S, Bhatia PK, Sethi P. Propofol infusion in an infant with glucose-6-phosphate dehydrogenase deficiency. J Anaesthesiol Clin Pharmacol. 2018;34:136-7

Födinger AM, Kammerlander C, Luger TJ. Ultrasound-Guided Regional Anesthesia in a Glucose-6-Phosphate Dehydrogenase (G6PD)-Deficient Geriatric Trauma Patient. Geriatr Orthop Surg Rehabil. 2012;3(4):147-9.

Goi T, Shionoya Y, Sunada K, Nakamura K. General Anesthesia in a Glucose-6-Phosphate Dehydrogenase Deficiency Child: A Case Report. Anesth Prog. 2019;66(2):94-6.

Bhaskaran S, Wakankar H. Single stage bilateral total knee arthroplasty in patient with G6PD deficiency. J Traum Orthopaed. 2015;10(1):25-6

Wang X, Qing Y, Hu T, Cong P, Wang X. Anesthetic Considerations of a Surgical Patient with Favism: A Case Report. J Blood Disord Transfus 2018;9:403.