Health related quality of life among adults living with sickle cell disease in Lagos, Nigeria

Authors

  • Akinsegun A. Akinbami Department of Hematology and blood transfusion, Faculty of Clinical Sciences, Lagos State University College of Medicine, Ikeja, Lagos, Nigeria
  • Olufunto O. Kalejaiye Department of Internal Medicine, College of Medicine, University of Lagos, Lagos, Nigeria
  • Ebele I. Uche Department of Hematology and blood transfusion, Faculty of Clinical Sciences, Lagos State University College of Medicine, Ikeja, Lagos, Nigeria
  • Olawale A. Kareem Department of Internal Medicine, Faculty of Clinical Sciences, Lagos State University College of Medicine, Ikeja, Lagos, Nigeria
  • Rafatu A. Bamiro Department of Hematology and blood transfusion, Faculty of Clinical Sciences, Lagos State University College of Medicine, Ikeja, Lagos, Nigeria
  • Benjamin Augustine Department of Hematology and Blood Transfusion, Faculty of Basic Clinical Sciences, Ahmadu Bello University, Zaria, Kaduna State, Nigeria
  • Hassan A. Odebiyi Department of Haematology, Federal Medical Centre, Birnin Kudu, Jigawa State, Nigeria
  • Abdul-Hafeez O. Balogun Newday Medical Centre, Akure, Ondo State, Nigeria

DOI:

https://doi.org/10.18203/issn.2454-2156.IntJSciRep20210542

Keywords:

Health related quality of life, WHOQOL-BREF, Sickle cell disease

Abstract

Background: Sickle cell disease (SCD) is an inherited haemoglobinopathy which involves the inheritance of haemoglobin S with any other abnormal haemoglobin from both parents. Health related quality of life (HRQOL) provides the patient’s view of his/her own wellbeing. This study was aimed at determining health related quality of life in SCD patients attending Lagos State University Teaching Hospital, Ikeja, Nigeria using the World Health organization quality of life-BREF (WHOQOL-BREF) questionnaire.  

Methods: This was a descriptive, cross sectional study in which an interviewer-administered WHOQOL-BREF questionnaire was used to assess health related quality of life of 250 SCD participants and 50 HbAA controls. The questionnaire assessment was based on physical, psychological, social and environmental domains. Data were analyzed using SPSS statistical software version 23.0. P value was considered to be statistically significant at<0.05.  

Results: Respondents mean age was 31.67±12.07 years. SCD participants scored generally lower than controls, regarding domains on physical, psychological and social health, however scores were at par on environmental domain. Physical health score was better in females with SCD than males, while males with SCD had a better social relationship than females. Psychological health and environment scores were almost equal in both males and females with SCD.

Conclusions: Health related quality of care is generally poor in SCD participants compared with HbAA controls, physical health is poorer in males with SCD than in females, however, psychological, social and environmental domains are similar in both genders.

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Author Biographies

Akinsegun A. Akinbami, Department of Hematology and blood transfusion, Faculty of Clinical Sciences, Lagos State University College of Medicine, Ikeja, Lagos, Nigeria

Professor, Department of Haematology and Blood Transfusion, Lagos State University College of Medicine. Ikeja. Lagos

Olufunto O. Kalejaiye, Department of Internal Medicine, College of Medicine, University of Lagos, Lagos, Nigeria

Lecturer 1

Department of Internal Medicine, College of Medicine, UNiversity of Lagos. Lagos

Ebele I. Uche, Department of Hematology and blood transfusion, Faculty of Clinical Sciences, Lagos State University College of Medicine, Ikeja, Lagos, Nigeria

Senior Lecturer, Department of Haematology and Blood Transfusion

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Published

2021-02-20

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Original Research Articles