Pre-pregnancy and prenatal care risk factors for spontaneous premature delivery in Western Uganda: a hospital based unmatched case-control study
DOI:
https://doi.org/10.18203/issn.2454-2156.IntJSciRep20211038Keywords:
Spontaneous premature delivery, Premature birth, Premature labor, Preterm birth, Preterm laborAbstract
Background: We aimed to establish pre-pregnancy and prenatal care risk factors for spontaneous premature delivery at Kampala international university teaching hospital (KIUTH) so as to enable us draw a platform upon which specific interventions can be formulated.
Methods: This was a hospital based unmatched case-control study conducted in the months of March to June 2019. A total of 110 cases and 330 controls admitted at KIUTH maternity and postnatal units were enrolled into the study. Interviewer administered questionnaires and respondent’s medical records were used to collect data. Chi square test and multiple logistic regression analysis were performed to establish the risk factors for spontaneous premature delivery at this facility. All data analyses were done using SPSS statistics version 20.
Results: Nulliparity, previous premature delivery, history of premature rupture of membranes, previous cervical procedures, history of not having received preconception care, urinary tract infections during pregnancy and maternal obesity were independently associated with spontaneous premature delivery at this hospital.
Conclusions: Guided by these factors, a high index of suspicion for spontaneous premature delivery among all pregnant women attending prenatal care is vital towards ameliorating this obstetric complication at KIUTH.
Metrics
References
Deressa AT, Cherie A, Belihu TM, Tasisa GG. Factors associated with spontaneous preterm birth in Addis Ababa public hospitals, Ethiopia: cross sectional study. BMC Pregnancy Childbirth. 2018;18(332):1-5.
Visser L, Boer MA De, Groot CJM De, Nijman TAJ, Hemels MAC, Bloemenkamp KWM, et al. Low dose aspirin in the prevention of recurrent spontaneous preterm labour-the APRIL study: a multicenter randomized placebo controlled trial. BMC Pregnancy Childbirth. 2017;17(223):1-7.
Hermans FJR, Schuit E, Opmeer BC, Oudijk MA, Bekker M, Woiski M, et al. Effectiveness of a cervical pessary for women who did not deliver 48 h after threatened preterm labor (Assessment of perinatal outcome after specific treatment in early labor: Apostel VI trial). BMC Pregnancy Childbirth. 2016;16(154):1-6.
Choi S. Use of progesterone supplement therapy for prevention of preterm birth : review of literatures. Obstet Gynecol Sci. 2017;60(5):405-20.
Tejada BM De. Maternal sepsis complicating arabin cervical pessary placement for the prevention of preterm birth: a case report. BMC Pregnancy Childbirth. 2017;17(34):4-7.
Oliver S, Uhm S, Duley L, Crowe S, David AL, James CP, et al. Top research priorities for preterm birth : results of a prioritisation partnership between people affected by preterm birth and healthcare professionals. BMC Pregnancy Childbirth. 2019;19(528):1-10.
Ha V, McDonald SD. Pregnant women’s preferences for and concerns about preterm birth prevention: a cross-sectional survey. BMC Pregnancy Childbirth. 2017;17(49):2-10.
Bernal AL. Preterm labour : mechanisms and management. BMC Pregnancy Childbirth. 2007;7(1):1-7.
Ayebare E, Ntuyo P, Malande OO, Nalwadda G. Maternal, reproductive and obstetric factors associated with preterm births in Mulago Hospital, Kampala, Uganda: a case control study. Pan Afr Med J. 2018;30(272):1-8.
Uganda Ministry of Health Clinical Guidelines. National Guidelines for Management of Common Conditions. 2016.
Wudie FT, Tesfamicheal FA, Fisseha HZ, Weldehawaria NB, Misgena KH, Alema HB, et al. Determinants of preterm delivery in the central zone of Tigray, northern Ethiopia: A case-control study. South African J Child Heal. 2019;13(3):108-14.
Chen K, Chen I, Yang Y, Chen K. The trends and associated factors of preterm deliveries from 2001 to 2011 in Taiwan. Medicine (Baltimore). 2019;98(13):1-6.
Delnord M, Blondel B, Prunet C, Zeitlin J. Are risk factors for preterm and early- term live singleton birth the same ? A population-based study in France. BMJ Open. 2018;8(e018745.):1-9.
Koullali B, Zijl MD Van, Kazemier BM, Oudijk MA, Mol BWJ, Pajkrt E, et al. The association between parity and spontaneous preterm birth : a population based study. BMC Pregnancy Childbirth. 2020;20(233):1-8.
Leal C, Esteves-pereira AP, Nakamura-pereira M, Torres JA, Theme-filha M, Maria R, et al. Prevalence and risk factors related to preterm birth in Brazil. Reprod Health. 2016;13(3):164-265.
Hidalgo-lopezosa P, Jiménez-ruz A, Carmona-torres JM. Sociodemographic factors associated with preterm birth and low birth weight: A cross-sectional study. Women and Birth. 2019;95(4):1-6.
Alijahan R, Hazrati S, Mirzarahimi M, Pourfarzi F, Hadi PA. Prevalence and risk factors associated with preterm birth in Ardabil, Iran. Iran J Reprod Med. 2014;12(1):47-56.
Ahumada-barrios ME, Alvarado GF. Risk Factors for premature birth in a hospital. Rev Lat Am Enferm. 2016;24(2750):1-8.
Shrestha S, Shrestha S, Shrestha US, Gyawali K. Predictors of Low Birth Weight at Lumbini Provincial Hospital, Nepal: A Hospital-Based Unmatched Case Control Study. Adv Prev Med. 2020;20(7):1-7.
Hamad KA, Abed Y, Hamad BA. Risk factors associated with preterm birth in the Gaza Strip: hospital based case-control study. East Mediterr Heal J. 2017;13(5):1132-40.
Huang S, Xia W, Sheng X, Qiu L, Zhang B, Chen T et al. Maternal lead exposure and premature rupture of membranes : a birth cohort study in China. BMJ Open. 2018;18(8):1-7.
Lee J, Romero R, Kim SM, Chaemsaithong P, Park W, Park JS et al. A new anti-microbial combination prolongs the latency period, reduces acute histologic chorioamnionitis as well as funisitis, and improves neonatal outcomes in preterm PROM. J Matern Neonatal Med. 2016;29(5):707-20.
Wagura P, Wasunna A, Laving A, Wamalwa D, Ng P. Prevalence and factors associated with preterm birth at kenyatta national hospital. BMC Pregnancy Childbirth. 2018;18(107):2-9.
Mahapula FA, Kumpuni K, Mlay JP, Mrema TF. Risk factors associated with pre-term birth in Dar es Salaam , Tanzania: a case-control study. Tanzan J Health Res. 2016;18(1):1-8.
Byonanuwe S, Nzabandora E, Nyongozi B, Pius T, Ayebare DS, Atuheire C et al. Predictors of Premature Rupture of Membranes among Pregnant Women in Rural Uganda: A Cross-Sectional Study at a Tertiary Teaching Hospital. Int J Reprod Med. 2020;2020(1862786):1-6.
Berretta R, Gizzo S, Asta AD, Mazzone E, Monica M, Franchi L, et al. Risk of Preterm Delivery Associated with Prior Treatment of Cervical Precancerous Lesion according to the Depth of the Cone. Dis Markers. 2013;35(6):721-6.
Sasieni P, Castanon A, Landy R, Kyrgiou M, Kitchener H, Quigley M et al. Risk of preterm birth following surgical treatment for cervical disease: executive summary of a recent symposium. BJOG. 2015;123(16):1426-9.
Su XJ, Huang SJ, Li X, Du QL. Prepregnancy Overweight and Obesity Are Associated with an Increased Risk of Preterm Birth in Chinese Women. Eur J Obes. 2020;13(237):237-44.
Slack E, Best KE, Rankin J, Heslehurst N. Maternal obesity classes, preterm and post-term birth: a retrospective analysis of 479, 864 births in England. BMC Pregnancy Childbirth. 2019;19(434):1-9.
Carcavalli L, Rocha IA, Valentim AF, Penido MG. Difference of Socioeconomic Factors among Mothers of Preterm and Full-Term Infant. Pesqui Bras Odontopediatria Clin Integr. 2020;20(5005):1-8.
Downloads
Published
How to Cite
Issue
Section
