Trichoepithelioma of thigh. Third reported case
Keywords:Trichoepithelioma, Basal cell carcinoma, Skin adnexal tumor, Brooke’s tumor
Trichoepithelioma a small benign tumor derived from basal cells in the hair follicle. A trichoepithelioma can undergo malignant transformation into the basal cell carcinoma. The recognition of trichoepithelioma is important because of its close resemblance to basal cell carcinoma and other skin adnexal tumors, both clinically and histopathologically. Here we present case of 40 year old male presenting with painless swelling in right thigh. Wide excision of swelling was done and sent for histopathology which showed the swelling to be trichoepithelioma.
Young AL, Kellermayer R, Szigeti R, Teszas A, Azmi S, Celebi JT. CYLD mutations underlie Brooke-Spiegler, Familial cylindromatosis, and multiple familial trichoepithelioma syndromes. Clin Genet. 2006;70:246-9.
Tatnall FM, Wilson-Jones E. Giant solitary trichoepithelioma located in the perianal area: a report of three cases. Br J Dermatol. 1986;115:91-9.
Filho GB, Toppa NH, Miranda D, Mattos MP, da Silva AL. Giant solitary trichoepithelioma. Arch Dermatol. 1984;120:797-8.
Czernobilskv B. Giant solitary trichoepithelioma. Arch Dermatol. 1972;105:587-8.
Brownstein MH, Shapiro L. Desmoplastic trichoepithelioma. Cancer. 1977;40:2979-86.
McDonald DM, Wilson JE, Marks R. Sclerosing epithelial hamartoma. Clin Exp Dermatol. 1977;2:153-6.
Dvir E. Solitary trichoepithelioma in a 70 year old man. Arch Dermatol. 1981;117:455-6.
Beck S, Cotton DW. Recurrent solitary giant trichoepithelioma located in the perianal area; a case report. Br J Dermatol. 1988;118:563-6.
Oursin C, Kruger HJ, Sigmund G, Hell Erich U. MR imaging of a giant solitary trichoepithelioma of the skin. Article in German. Radiologe. 1991;31:574-6.
Jemec B, Lovgreen Nielsen P, Jemec GB, Balser E. Giant solitary trichoepithelioma. Dermatol Online J. 1999;5:1.
Krishnamurthy J, Diva K. The cytology of giant solitary trichoepithelioma. J Cytol. 2010;27:99-101.
Goyal S, Mahajan NC, Garg M, Goyal S. Giant solitary nodular trichoepithelioma: a case report and review of literature. Arch of Clin Surg. 2012;1:58-60.
Muruganantham Arunagirinathan, K. R. Mohan, J. Sivaraman, S. Ashok. Case report on giant solitary trichoepithelioma. Int J Clin Cases Invest. 2014;6:20-5.
Brooke JD, Fitzpatrick JE, Golitz LE. Papillary mesenchymal bodies: a histologic finding useful in differentiating trichoepitheliomas from basal cell carcinomas. J Am Acad Dermatol. 1989;21:523-8.
Hundeiker M, Berger H. Zur morphogenese der basaliome. Arch Klin Exp Dermatol. 1968;231:161.
Foot NC. Adnexal carcinoma of the skin. Am J Pathol. 1947;23:1.